I'm so drug-resistant in general, that it didn't come as much of a surprise to me. I've taken every opiate and NSAID commonly available at one time or another and nothing has ever touched any pain I've ever had. Not even a morphine pump. When I had my testicular torsion a couple weeks ago, I turned down Toradol shots twice because I knew it was just a waste of time. As far as weed goes, I've tried it several times, and the only thing to ever effect me was edibles, and the effect of that was just like drinking six beers after eating four of them over the course of an hour.