Antidepressants in water trigger autism genes...

KRSOne

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#1
in fish

Maybe its not the vaccines.

Updated 16:31 07 June 2012 by Sara Reardon
Low levels of antidepressants and other psychoactive drugs in water supplies can trigger the expression of genes associated with autism – in fish at least.

The use of antidepressants has increased dramatically over the past 25 years, says Michael Thomas of Idaho State University in Pocatello. Around 80 per cent of each drug passes straight through the human body without being broken down, and so they are present in waste water. In most communities, water purification systems cannot filter out these pharmaceuticals. "They just fly right through," says Thomas, which means they ultimately find their way into the water supply.

The concentration of these drugs in drinking water is very low – at most, they are present at levels several orders of magnitude lower than the prescription doses. But since the drugs are specifically designed to act on the nervous system, Thomas hypothesised that even a small dose could affect a developing fetus.

Thomas's group created a cocktail of the anti-epileptic drug carbamazepine and two selective serotonin uptake inhibitor (SSRI) antidepressants, fluoxetine and venlafaxine, at this low concentration. They exposed fathead minnows (Pimephales promelas) to the drugs for 18 days, then analysed the genes that were being expressed in the fishes' brains.

Although the researchers had expected the drugs might activate genes involved in all kinds of neurological disorders, only 324 genes associated with autism in humans appeared to be significantly altered. Most of these genes are involved in early brain development and wiring.

The finding fits with previous research which had found that pregnant women who take SSRIs are slightly more likely to have autistic children. (Archives of General Psychiatry, DOI: 10.1001/archgenpsychiatry.2011.73).

To test whether these changes actually altered the fish's behaviour, the researchers did an experiment in which they startled the fish. Fish exposed to the drugs tended to panic and behave differently from a control group of fish.

Thomas emphasises that the research is very preliminary – there's no need for pregnant women to worry about their drinking water yet, he says. The researchers next plan to study whether the drugs have a similar effect in mammals. They are testing this by lacing the drinking water of pregnant mice with the low-concentration cocktail. They are also studying water supplies in areas around the country where there are particularly high concentrations of drugs to determine whether the fish – and people – in these areas have autism-like gene expression patterns.
 

NuttyJim

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You can hypothesize alot of ideas, the thing is CAN YOU PROVE IT?
 

KRSOne

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I wonder if my water filter takes out all that stuff.... Do I have to go back to estrogen water?
 

Yesterdays Hero

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#4
You can hypothesize alot of ideas, the thing is CAN YOU PROVE IT?
Doesn't matter what his original post was, and it doesn't matter what his following post from yours was. He just answered you 'No.' without typing it.

The joys of being able to understand Kirk while having him on Ignore. :D
 

justifyyourgarb

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#5
Low levels of antidepressants and other psychoactive drugs in water supplies can trigger the expression of genes associated with autism
I don't think water is what made you autistic, Kirk.
 

justifyyourgarb

You drab South Bend cocksuckers are all the same.
Mar 15, 2007
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#8
My parents did shoot me up with all the vaccines as a kid so you may be right.
I don't think that had as much to do with it as poor parenting and shit genes.
 

Mags

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My parents did shoot me up with all the vaccines as a kid so you may be right.
How's that basement in the Summer, damp? Or does Mommy turn on the air conditioning?
 

Creasy Bear

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The finding fits with previous research which had found that pregnant women who take SSRIs are slightly more likely to have autistic children. (Archives of General Psychiatry, DOI: 10.1001/archgenpsychiatry.2011.73).
I can spot a confounding factor right off the bat...

Rich white wimmens are the ones glomming all of the SSRIs, and it's rich white wimmens that tend to be all obsessed with every fart and hiccup that comes out of their precious little snowflakes... and it's rich white wimmens who tend to demand that their kids be labeled "autistic" and therefore "special"... rather than just accept the fact that their brats are just annoying dummies.

So it's probably not a matter of the SSRI's the mothers are taking are making their kids autistic. It's probably a matter that mothers who are on SSRI's are the types of women who seek out a diagnosis of "autistic" for their kids.

Po' black wimmens don't generally take SSRI's(cuz they can't affowd it), and po' black wimmens are perfectly content to accept the fact that their children are just plain ol' dummies... while rich white wimmens pop SSRI's like they're jellybeans, and rich white wimmens will never accept that their children are anything other than "special".

That's what's known as a "confounding social demographic factor" in the medical research game... and they should always be considered and adjusted for whenever a researcher starts throwing hypothesiseseseses around.
 

Creasy Bear

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#12
I wonder if my water filter takes out all that stuff.... Do I have to go back to estrogen water?
Estrogen water? Is that what your mother called it when she was still breastfeeding you well into your teens?

"Time for your estrogen water num nums, Kirky."
 

Hoffman

Guess who's back? Hoffman's back
Sep 28, 2006
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#14
Let's see...an article on autism by newscientist.com. A "science" website that ISN'T peer reviewed. Yeah, I'm sure they're research is top notch over there.
 

Norm Stansfield

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Mar 17, 2009
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Thomas hypothesised that even a small dose could affect a developing fetus.
Facts:
1. All known teratogens (big word for someone obessed with fake science, I know: they're agents that cause birth defects) associated with autism act withing the first 8 weeks of conception.
2. Fetal development in humans starts at 11 weeks. So what the fake scientist should be fake hypothesizing is that his fake study points to the fake conclusion that a developing embryo could be affected. Not a fetus.
 

Norm Stansfield

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#16
The finding fits with previous research which had found that pregnant women who take SSRIs are slightly more likely to have autistic children. (Archives of General Psychiatry, DOI: 10.1001/archgenpsychiatry.2011.73).
You should've clicked the link, buddy. The study you have linked to did not find that pregnant women who take SSRIs are slightly more likely to have autistic children. That's a lie.

What the study found it that these women MAY be slightly more likely to have autistic children. From the link
Although the number of children exposed prenatally to selective serotonin reuptake inhibitors in this population was low, results suggest that exposure, especially during the first trimester, may modestly increase the risk of ASD. The potential risk associated with exposure must be balanced with the risk to the mother or fetus of untreated mental health disorders. Further studies are needed to replicate and extend these findings.
Instead of performing those studies, to confirm the preliminary findings, your fake scientist just extended them from "may" to "is", because it suited his agenda. You suck, Kirk. You are incapable of distinguishing science from fiction. Stop spreading this nonsense, and work on that instead. Fucking pick up a science manual and learn something.
 

ShooterMcGavin

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When I saw the title of this thread I immediately knew who posted it and actually muttered, "Oh, Gawwdd" while face palming.
 
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BIV

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Autism Gene? Fuck I know that dude. He used to roll with Influenza Fred and Leprosy Dave.

Nice enough dude, and strong as fuck. Not too bright, tho.
 

Creasy Bear

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My parents did shoot me up with all the vaccines as a kid.
Congratulations, you've finally provided solid evidence which supports the hypothesis that childhood vaccination causes mental deficiencies.
 

jimmyslostchin

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Autism Gene? Fuck I know that dude. He used to roll with Influenza Fred and Leprosy Dave.

Nice enough dude, and strong as fuck. Not too bright, tho.
Didn't he also go by the stage name "Mean Gene The Autism Machine?"
 

Motor Head

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#24
I can spot a confounding factor right off the bat...

Rich white wimmens are the ones glomming all of the SSRIs, and it's rich white wimmens that tend to be all obsessed with every fart and hiccup that comes out of their precious little snowflakes... and it's rich white wimmens who tend to demand that their kids be labeled "autistic" and therefore "special"... rather than just accept the fact that their brats are just annoying dummies.

So it's probably not a matter of the SSRI's the mothers are taking are making their kids autistic. It's probably a matter that mothers who are on SSRI's are the types of women who seek out a diagnosis of "autistic" for their kids.

Po' black wimmens don't generally take SSRI's(cuz they can't affowd it), and po' black wimmens are perfectly content to accept the fact that their children are just plain ol' dummies... while rich white wimmens pop SSRI's like they're jellybeans, and rich white wimmens will never accept that their children are anything other than "special".

That's what's known as a "confounding social demographic factor" in the medical research game... and they should always be considered and adjusted for whenever a researcher starts throwing hypothesiseseseses around.
A cousin of mine has a son that is "special". She coddles his dumbass and lets him act up constantly. She brought him to my 4th of July pool party last year and I caught him throwing landscaping rock at the side of my house and I yelled at his stupid ass. The rest of the day, he was quiet and well behaved. Who knew that simply having a man scream at him to stop being a fucking retard would work miracles. My nephew is being raised by a single mother. He completely ignores his mother and is turning into quite the little hoodlum. He comes around here and he is perfectly behaved for fear I will kick his ass.

I think a lot of cases of ADD and autism can be cured by a male role model that is willing to beat their ass if the situation calls for it. My dad was a great guy, but if I started acting like an asshole - he'd kick my ass.