This kind of poster has been repeatedly parodied; for example, "Despair, Inc." offers a series of Demotivators posters, as well as a "Parody Motivator Generator" which allows users to produce their own posters from a base image an "Poster Forge" which also allows to print generated posters in wall size.
One famous motivational poster features a kitten hanging from a tree branch along with the phrase "Hang in There, Baby!" This poster has also been the target of various reproductions and parodies, such as an appearance on an episode of The Simpsons where Marge Simpson notices the copyright date (1968) and comments, "...determined or not, that cat must be long dead. That's kind of a downer.". Another reference to the poster is The Onion's "In the News" photograph titled "Inspirational Poster Kitten Falls To Death After 17 Years".