Disclaimer: I am not asking which drugs inspire or cause the best music, but which drugs are associated with your favorite music? Also, I'm pretty high right now. Heroin makes a strong statement, with jazz greats like Charlie Parker, John Coltrane and Miles Davis, along with punk icons like Dee Dee Ramone, Johnny Thunders, Sid Vicious, Iggy Pop, Lou Reed, and the great Kurt Cobain. Cocaine gives us the early blues geniuses and late 1970's David Bowie, but also gave us Def Leppard and Poison. I'd say it's a wash. Weed: Pretty much everyone, so a good choice. The Beatles (I could stop right there), Jimi Hendrix, Beastie Boys, Simon & Garfunkel, A Tribe Called Quest. Crystal meth: Um, Brokencyde? Alcohol: Uhh, maybe Bruce Springsteen? I didn't really think about it.